Written by:
Dr. Sophie Reynolds
Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing
Avonza Tablet
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Benefits
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Reduces HIV viral load to undetectable levels (with good adherence)
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Boosts immune system (increases CD4 count)
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Convenient once-daily dosing
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Helps prevent HIV-related infections
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Proven first-line therapy recommended worldwide
Indications and Usage
Avonza Tablet is indicated for:
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HIV-1 infection in adults and adolescents
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First-line ART regimen
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Long-term viral suppression and immune improvement
It does not cure HIV but helps manage it effectively.
How it Works
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Tenofovir + Lamivudine: Block reverse transcriptase, preventing HIV from multiplying.
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Efavirenz: Reduces viral replication and boosts effectiveness of the combination.
Together, they suppress HIV growth and allow the immune system to recover.
Dosage & Administration
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Usual dose: One tablet once daily, preferably at bedtime
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Take on an empty stomach to reduce side effects
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Swallow whole with water
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Do not skip doses — adherence is critical
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Regular viral load and CD4 monitoring required
Do not stop treatment without medical advice.
Side Effects
Common side effects:
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Dizziness
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Vivid dreams or sleep disturbances
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Nausea
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Headache
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Rash
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Fatigue
Serious side effects (seek urgent care):
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Severe liver or kidney problems
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Lactic acidosis
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Severe rash or allergic reaction
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Mental health changes (anxiety, depression)
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Persistent abdominal pain or yellowing of skin/eyes
Warning and Precaution
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Not recommended during pregnancy unless advised
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Use caution in patients with kidney or liver disease
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Efavirenz may cause dizziness — avoid driving initially
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Does not prevent HIV transmission — safe protection needed
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Inform doctor about all medicines, including herbal supplements
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Report severe rash, mood changes, or breathing difficulty immediately
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