Written by:
Dr. Sophie Reynolds

Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing

Avonza Tablet

Brand Name:   Avonza
Molecule:   Efavirenz, Lamivudine, Tenofovir
Strength:   1000 mg
Quantity:   30 Tablets
Form:   Tablet
Packaging Type:   Bottle
Manufacturer/Marketed By:   Mylan
Country of Origin:   India
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Benefits

  • Reduces HIV viral load to undetectable levels (with good adherence)

  • Boosts immune system (increases CD4 count)

  • Convenient once-daily dosing

  • Helps prevent HIV-related infections

  • Proven first-line therapy recommended worldwide

Indications and Usage

Avonza Tablet is indicated for:

  • HIV-1 infection in adults and adolescents

  • First-line ART regimen

  • Long-term viral suppression and immune improvement

It does not cure HIV but helps manage it effectively.

How it Works

  • Tenofovir + Lamivudine: Block reverse transcriptase, preventing HIV from multiplying.

  • Efavirenz: Reduces viral replication and boosts effectiveness of the combination.

Together, they suppress HIV growth and allow the immune system to recover.

Dosage & Administration

  • Usual dose: One tablet once daily, preferably at bedtime

  • Take on an empty stomach to reduce side effects

  • Swallow whole with water

  • Do not skip doses — adherence is critical

  • Regular viral load and CD4 monitoring required

Do not stop treatment without medical advice.

Side Effects

Common side effects:

  • Dizziness

  • Vivid dreams or sleep disturbances

  • Nausea

  • Headache

  • Rash

  • Fatigue

Serious side effects (seek urgent care):

  • Severe liver or kidney problems

  • Lactic acidosis

  • Severe rash or allergic reaction

  • Mental health changes (anxiety, depression)

  • Persistent abdominal pain or yellowing of skin/eyes

Warning and Precaution

  • Not recommended during pregnancy unless advised

  • Use caution in patients with kidney or liver disease

  • Efavirenz may cause dizziness — avoid driving initially

  • Does not prevent HIV transmission — safe protection needed

  • Inform doctor about all medicines, including herbal supplements

  • Report severe rash, mood changes, or breathing difficulty immediately

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