Written by:
Dr. Sophie Reynolds

Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing

Abamune-l Tablets Tablet

Brand Name:   Abamune-L
Molecule:   Abacavir, Lamivudine
Strength:   900 mg
Quantity:   30 Tablets
Form:   Tablet
Packaging Type:   Bottle
Manufacturer/Marketed By:   Cipla
Country of Origin:   India

Description

Abamune-L Tablet contains Abacavir and Lamivudine, two antiviral medicines used to treat HIV-1 infection. It helps reduce viral load, strengthen immunity, and improve long-term treatment outcomes when taken consistently.

Benefits

  • Significantly lowers HIV viral load

  • Helps increase CD4 cell count

  • Reduces risk of opportunistic infections

  • Once-daily dosing improves treatment adherence

  • Recommended in many WHO and NACO ART regimens

Indications and Usage

  • Management of HIV-1 infection in adults and adolescents

  • Used as part of a combination ART regimen

  • Helps achieve and maintain viral suppression

Note: This medicine does not cure HIV but helps manage the infection effectively.

How it Works

Abacavir and Lamivudine inhibit the reverse transcriptase enzyme, which is essential for HIV replication. By blocking viral multiplication, the medicine reduces viral load and helps the immune system recover.

Dosage & Administration

  • Typically one tablet once daily, or as prescribed

  • Take at the same time every day for best results

  • Do not skip doses—this may lead to resistance

  • A HLA-B*5701 test is recommended before starting Abacavir to avoid hypersensitivity

  • Regular monitoring of viral load and CD4 count is essential

Side Effects

Common side effects:

  • Headache

  • Fatigue

  • Nausea, vomiting

  • Fever

  • Diarrhea

Serious side effects (seek medical help):

  • Hypersensitivity reaction (associated with Abacavir)

  • Liver problems

  • Lactic acidosis

  • Severe skin rash

  • Breathing difficulty

Warning and Precaution

  • Avoid if HLA-B*5701 positive

  • Use cautiously in liver or kidney disease

  • Not recommended with alcohol

  • Discuss safety during pregnancy and breastfeeding with a doctor

  • Does not prevent HIV transmission—safe practices required

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