Written by:
Dr. Sophie Reynolds

Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing

Alkixen 250 mg Capsule

Brand Name:   Alkixen
Molecule:   Crizotinib
Strength:   250 mg
Quantity:   60 Capsules
Form:   Capsule
Packaging Type:   Bottle
Manufacturer/Marketed By:   Everest Pharma
Country of Origin:   Bangladesh

Description

Alkixen Crizotinib 250 mg Capsule contains Crizotinib, a targeted cancer medicine used to treat ALK-positive and ROS1-positive metastatic non-small cell lung cancer (NSCLC). It helps slow tumor growth and spread under oncologist supervision.

Benefits

  • Targets specific genetic drivers of lung cancer

  • Helps slow tumor growth and spread

  • Can improve progression-free survival

  • Effective oral therapy with convenient dosing

  • Beneficial in patients intolerant or resistant to prior therapies

Indications and Usage

Alkixen Crizotinib 250 mg Capsule is indicated for:

  • ALK-positive metastatic non-small cell lung cancer (NSCLC)

  • ROS1-positive metastatic NSCLC

Diagnosis must be confirmed through approved biomarker testing, and treatment supervised by an oncologist.

How it Works

Crizotinib blocks abnormal ALK and ROS1 tyrosine kinase receptors, which drive uncontrolled cancer cell growth. By inhibiting these signaling pathways, it slows cancer progression and reduces tumor activity.

Dosage & Administration

  • Typical adult dose: 250 mg twice daily, or as prescribed

  • Swallow capsule whole with water

  • Take with or without food, at the same time daily

  • Do not crush, chew, or open the capsule

  • Do not skip or double doses

  • Requires routine liver tests, ECGs, and clinical monitoring

Use only under oncologist guidance.

Side Effects

Common side effects:

  • Nausea or vomiting

  • Diarrhea or constipation

  • Vision disturbances

  • Fatigue

  • Swelling in hands or feet

  • Loss of appetite

Serious side effects (seek immediate care):

  • Liver toxicity

  • Lung inflammation (pneumonitis)

  • Irregular heartbeat

  • Severe abdominal pain

  • Severe dizziness or fainting

Warning and Precaution

  • Not recommended during pregnancy or breastfeeding

  • Use caution in patients with liver disease, heart rhythm disorders, or kidney issues

  • Avoid grapefruit or grapefruit juice (may increase drug levels)

  • Report shortness of breath, chest pain, yellowing of skin/eyes, or severe visual changes

  • Inform doctor about all ongoing medicines to avoid interactions

  • Avoid driving if experiencing dizziness or blurred vision

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