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Alpesib 150 mg Tablet

Brand Name: Alpesib

Molecule: Alpelisib

Strength: 150 mg

Quantity: 28 Tablets

Form: Tablet

Packaging Type: Bottle

Manufacturer/Marketed By: Everest Pharma

Country of Origin: Bangladesh

Description

Alpesib 150 mg Tablet contains Alpelisib, a targeted anticancer medicine used to treat certain types of breast cancer. It helps slow tumor growth in patients with PIK3CA-mutated, HR-positive, HER2-negative disease under oncologist supervision.

Benefits

Targets tumors with PIK3CA mutation
Helps slow cancer growth and spread
May improve progression-free survival
Oral targeted therapy for convenient dosing
Effective after endocrine therapy resistance

Indications and Usage

Alpesib 150 mg Tablet is indicated for:

HR-positive, HER2-negative metastatic or advanced breast cancer
Confirmed PIK3CA gene mutation
Used in combination with fulvestrant
For postmenopausal women and adult men after prior endocrine therapy

Diagnosis and treatment must be supervised by an oncologist.

How it Works

Alpelisib selectively inhibits the PI3K-alpha pathway, which is overactive in cancers with PIK3CA mutations. By blocking this signaling, it reduces cancer cell growth, survival, and resistance to hormonal therapy.

Dosage & Administration

Typical dose: 150 mg once daily, or as prescribed
Taken with food, at the same time each day
Swallow tablets whole—do not crush, chew, or break
Continue therapy unless disease progression or intolerance occurs
Requires routine monitoring of blood sugar, liver function, and skin reactions
Do not adjust or stop dose without oncologist approval

Side Effects

Common side effects:

High blood sugar (hyperglycemia)
Diarrhea
Rash or itching
Nausea
Fatigue
Loss of appetite

Serious side effects (seek urgent help):

Severe allergic or skin reactions
Lung inflammation (pneumonitis)
Severe hyperglycemia or ketoacidosis
Liver dysfunction
Dehydration

Warning and Precaution

Not recommended during pregnancy or breastfeeding
Use caution in patients with diabetes — high risk of hyperglycemia
Monitor liver, kidney, and lung function regularly
Avoid alcohol and high-sugar foods if blood sugar increases
Inform doctor about all ongoing medications
Stop treatment and seek help if severe rash, breathing issues, or extreme fatigue occur