Acabrunat 100 mg Capsule

Brand Name: Acabrunat

Molecule: Acalabrutinib

Strength: 100 mg

Quantity: 30 Capsule

Form: Capsule

Packaging Type: Bottle

Manufacturer/Marketed By: Natco Pharma

Country of Origin: India

Description

Acabrunat 100 mg Capsule contains Acalabrutinib, a targeted anticancer medicine used to treat certain blood cancers. It helps slow cancer cell growth and disease progression under specialist supervision.

Benefits

Targets malignant B-cell pathways
Helps slow cancer growth and spread
Can improve progression-free survival
Oral capsule ensures convenient administration
Effective treatment option in modern hematologic oncology

Indications and Usage

Acabrunat 100 mg Capsule is indicated for:

Mantle Cell Lymphoma (MCL) in adults previously treated
Chronic Lymphocytic Leukemia (CLL)
Small Lymphocytic Lymphoma (SLL)

Treatment must be initiated and supervised by an experienced oncologist.

How it Works

Acalabrutinib selectively inhibits Bruton Tyrosine Kinase (BTK), an enzyme essential for cancerous B-cell survival and multiplication. By blocking BTK signaling, it helps slow tumor growth and disease progression.

Dosage & Administration

Usual adult dose: 100 mg twice daily, or as prescribed
Swallow capsule whole with water
Take at the same times every day
Do not crush, chew, or open the capsule
Do not skip or double doses
Requires routine blood tests and clinical monitoring

Use only under oncologist guidance.

Side Effects

Common side effects:

Headache
Fatigue
Diarrhea
Muscle or joint pain
Easy bruising or bleeding

Serious side effects:

Severe bleeding
Serious infections
Irregular heartbeat (atrial fibrillation)
Secondary cancers
Low blood cell counts

Seek immediate medical care if symptoms worsen.

Warning and Precaution

Not recommended during pregnancy or breastfeeding
Use cautiously in patients with bleeding disorders, heart problems, or liver disease
Avoid live vaccines during treatment
Increased infection risk — report fever or weakness immediately
Inform doctor about blood thinners or ongoing medications
Stop and seek help if allergic or hypersensitivity symptoms develop

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January 30, 2025

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