Ascimib 40 mg Tablet
Brand Name: Ascimib
Molecule: Asciminib
Strength: 40 mg
Quantity: 30 Tablets
Form: Tablet
Packaging Type: Bottle
Manufacturer/Marketed By: Everest Pharma
Country of Origin: Bangladesh
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Description
Ascimib Asciminib 40 mg Tablet contains Asciminib, a targeted therapy used to treat Philadelphia chromosome–positive chronic myeloid leukemia (Ph+ CML). It helps control cancer cell growth in patients resistant or intolerant to previous treatments.
Benefits
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Targets CML cells with high precision
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Effective in patients resistant to multiple TKIs
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Helps achieve and maintain molecular remission
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Oral therapy for convenient long-term treatment
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Lower risk of some TKI-related side effects
Indications and Usage
Ascimib Asciminib 40 mg Tablet is indicated for:
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Ph+ Chronic Myeloid Leukemia (CML) — Chronic Phase
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Patients previously treated with at least one TKI
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Patients resistant or intolerant to prior CML therapies
Therapy must be prescribed and managed by a hematologist/oncologist.
How it Works
Asciminib uniquely targets the ABL myristoyl pocket, blocking BCR-ABL1 signaling responsible for leukemia cell growth. This disrupts cancer cell survival and slows disease progression while sparing healthy cells.
Dosage & Administration
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Typical dose: 40 mg once or twice daily, or as prescribed
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Take with or without food, at the same time daily
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Swallow tablets whole—do not crush or chew
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Do not skip or double doses
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Regular blood tests and clinical monitoring required
Use only under oncologist supervision.
Side Effects
Common side effects:
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Fatigue
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Nausea
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Headache
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Joint or muscle pain
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Rash
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Low blood counts
Serious side effects (seek urgent care):
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High blood pressure
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Pancreatitis
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Severe myelosuppression
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Heart-related symptoms
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Severe allergic reactions
Warning and Precaution
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Not recommended during pregnancy or breastfeeding
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Use cautiously in patients with hypertension or pancreatic disease
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Monitor blood counts, liver enzymes, and blood pressure regularly
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Inform doctor about all current medications to avoid interactions
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Report abdominal pain, unusual fatigue, bleeding, or chest pain immediately
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