Written by:
Dr. Sophie Reynolds

Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing

Abec-L Tablets Tablet

Brand Name:   Abec-L
Molecule:   Abacavir, Lamivudine
Strength:   900 mg
Quantity:   30 Tablets
Form:   Tablet
Packaging Type:   Bottle
Manufacturer/Marketed By:   Emcure Pharmaceuticals
Country of Origin:   India

Description

Abec-L Tablet contains Abacavir and Lamivudine, two antiretroviral medicines used for managing HIV-1 infection. It helps lower viral load, strengthen immunity, and support long-term HIV control.

Benefits

  • Reduces HIV viral load

  • Increases CD4 cell count

  • Improves immune function

  • Helps prevent opportunistic infections

  • Once-daily tablet improves treatment adherence

Indications and Usage

  • Treatment of HIV-1 infection in adults and adolescents

  • Used along with other antiretroviral medicines as part of combination ART

  • Helps maintain viral suppression and reduce disease progression

Note: This medicine does not cure HIV but helps control it effectively with regular use.

How it Works

Abacavir and Lamivudine block the reverse transcriptase enzyme, which HIV needs to replicate. By preventing viral multiplication, the medicine lowers viral load and allows the immune system to strengthen.

Dosage & Administration

  • Typically one tablet once daily, or as directed by the doctor

  • Can be taken with or without food

  • Do not miss doses—adherence is essential to prevent resistance

  • HLA-B*5701 test is recommended before starting Abacavir

  • Regular viral load and CD4 count monitoring is required

Side Effects

Common side effects:

  • Headache

  • Fatigue

  • Fever

  • Nausea or vomiting

  • Diarrhea

Serious side effects (seek urgent attention):

  • Abacavir hypersensitivity reaction

  • Lactic acidosis

  • Liver problems

  • Severe skin rash

  • Breathing difficulty or chest pain

Warning and Precaution

  • Do not use if HLA-B*5701 positive due to hypersensitivity risk

  • Use with caution in patients with liver or kidney disease

  • Avoid alcohol to reduce liver stress

  • Inform your doctor if pregnant or breastfeeding

  • Does not prevent HIV transmission—safe sex and infection-control practices required

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