Imbruvica 140 mg Capsule

Brand Name: Imbruvica

Molecule: Ibrutinib

Strength: 140 mg

Quantity: 30 Capsules

Form: Capsule

Packaging Type: Bottle

Manufacturer/Marketed By: Johnson Amp Johnson Private Limited

Description

Imbruvica 140 mg Capsule contains Ibrutinib, a targeted cancer therapy used to treat certain blood cancers. It works by blocking signals that help cancer cells grow and survive, thereby slowing disease progression. Treatment should be taken under the supervision of an oncologist or hematologist.

Benefits

Targets cancer-causing B-cell signaling pathways
Helps slow cancer progression and improve survival
Oral capsule allows convenient daily dosing
Effective across multiple B-cell malignancies
Suitable for long-term disease management

Indications and Usage

Imbruvica 140 mg Capsule is indicated for:

Chronic Lymphocytic Leukemia (CLL)
Small Lymphocytic Lymphoma (SLL)
Mantle Cell Lymphoma (MCL) (after prior therapy)
Waldenström’s Macroglobulinemia
Marginal Zone Lymphoma (MZL) (after prior treatment)
Chronic Graft-Versus-Host Disease (cGVHD) (selected patients)

Treatment must be prescribed and monitored by a specialist.

How it Works

Ibrutinib inhibits Bruton’s Tyrosine Kinase (BTK), a key enzyme involved in the survival and proliferation of malignant B-cells. By blocking BTK signaling, Imbruvica helps stop cancer cell growth and induces cancer cell death.

Dosage & Administration

Dosage depends on the condition being treated and doctor’s advice
Common regimens range from 420 mg to 560 mg daily (multiple 140 mg capsules)
Take capsules once daily, at the same time each day
Swallow capsules whole with water
Do not open, crush, or chew
Do not stop or adjust dose without medical advice

Side Effects

Common side effects:

Diarrhea
Fatigue
Nausea
Muscle or joint pain
Rash
Bruising

Serious side effects (seek medical attention):

Serious bleeding
Heart rhythm problems (atrial fibrillation)
Severe infections
High blood pressure
Low blood cell counts

Warning and Precaution

Not recommended during pregnancy or breastfeeding
Increased risk of bleeding — caution if taking blood thinners
Monitor heart rhythm, blood pressure, and blood counts regularly
Use caution in patients with heart disease or infection risk
Avoid grapefruit and Seville oranges during treatment
Inform doctor about all medicines and supplements
Report chest pain, irregular heartbeat, severe bleeding, or infection symptoms immediately