BD Zadine 300 mg Tablet

Brand Name: BD-Zadine

Molecule: Azacitidine

Strength: 300 mg

Quantity: 14 Tablets

Form: Tablet

Packaging Type: Bottle

Country of Origin: India

Description

BD Zadine 300 mg Tablet is a prescription medicine containing Azacitidine, a hypomethylating agent used to treat disorders where the bone marrow does not produce healthy blood cells. It is commonly prescribed for myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML), and selected cases of acute myeloid leukemia (AML). The medicine helps reduce transfusion needs, supports healthy cell production, and slows disease progression.

Benefits

Improves production of healthy blood cells
Reduces dependence on blood transfusions
Slows progression of bone marrow disorders
Enhances survival and quality of life
Convenient oral alternative to injectable azacitidine

Indications and Usage

BD Zadine 300 mg Tablet is indicated for:

Myelodysplastic Syndromes (MDS)
Chronic Myelomonocytic Leukemia (CMML)
Acute Myeloid Leukemia (AML) (specific patient groups)
Patients with abnormal, ineffective, or reduced blood cell production

How it Works

Azacitidine reduces abnormal DNA methylation, restoring normal functioning of bone marrow cells. This slows the growth of immature or cancerous cells and supports healthier blood formation.

Dosage & Administration

Dose is customized by the treating oncologist
Swallow the tablet whole with water
Take exactly as per prescribed treatment cycles
Do not crush, chew, or break the tablet
Regular blood tests required to monitor safety and response
Do not skip or stop treatment without medical advice

Side Effects

Common side effects:

Fatigue, weakness
Nausea, vomiting
Constipation or diarrhea
Loss of appetite
Low blood counts (anemia, neutropenia, thrombocytopenia)

Serious side effects (seek urgent care):

Fever or signs of infection
Unusual bleeding or bruising
Severe abdominal pain
Kidney or liver dysfunction
Severe allergic reactions

Warning and Precaution

Not recommended during pregnancy or breastfeeding
Increased risk of infection due to low immunity
Use cautiously in patients with kidney or liver disease
Avoid contact with sick individuals
Report immediately:
- Fever or chills
- Unusual bleeding
- Yellowing of skin or eyes
- Chest pain or breathing difficulty
Inform doctor about all chemotherapy or immunosuppressive drugs being used

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