Written by:
Dr. Sophie Reynolds

Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing

Azarest 300 mg Tablet

Brand Name:   Azarest
Molecule:   Azacitidine
Strength:   300 mg
Quantity:   14 Tablets
Form:   Tablet
Packaging Type:   Bottle
Manufacturer/Marketed By:   Everest Pharma
Country of Origin:   Bangladesh

Description

Azarest 300 mg Tablet contains Azacitidine, an anticancer medicine used to treat myelodysplastic syndromes (MDS) and certain types of leukemia. It helps improve bone marrow function and slows the growth of abnormal blood cells under specialist supervision.

Benefits

  • Improves production of healthy blood cells

  • Reduces transfusion requirement

  • Slows disease progression

  • Enhances quality of life in MDS patients

  • Convenient oral formulation for long-term therapy

Indications and Usage

Azarest 300 mg Tablet is indicated for:

  • Myelodysplastic Syndromes (MDS)

  • Chronic Myelomonocytic Leukemia (CMML)

  • Acute Myeloid Leukemia (AML) (selected patients)

  • Patients with ineffective or insufficient blood cell production

How it Works

Azacitidine reduces abnormal DNA methylation, restoring normal gene expression and slowing the uncontrolled growth of immature blood cells. This helps the bone marrow produce healthier and more functional blood cells.

Dosage & Administration

  • Dose determined individually by the oncologist

  • Swallow tablet whole with water

  • Follow exact treatment cycles prescribed

  • Do not crush or chew the tablet

  • Regular blood tests required to monitor counts and organ function

  • Avoid missed doses for best results

Use only under medical supervision.

Side Effects

Common side effects:

  • Nausea, vomiting

  • Fatigue or weakness

  • Diarrhea or constipation

  • Loss of appetite

  • Low blood counts (neutropenia, anemia, thrombocytopenia)

Serious side effects (seek urgent care):

  • Severe infection or fever

  • Unusual bleeding or bruising

  • Kidney or liver impairment

  • Allergic reactions

  • Shortness of breath or chest discomfort

Warning and Precaution

    • Not safe during pregnancy or breastfeeding

    • May cause severe bone marrow suppression — monitor counts regularly

    • Caution in patients with kidney or liver problems

    • Avoid contact with sick individuals due to infection risk

    • Report immediately:

      • Fever or persistent infection

      • Unexplained bleeding

      • Extreme fatigue

      • Yellowing of skin/eyes

      • Chest pain or breathing issues

    • Inform doctor about all chemotherapy or immunosuppressive medicines

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