Written by:
Dr. Sophie Reynolds
Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing
Alimta 100 mg Injection
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Description
Alimta 100mg Injection contains Pemetrexed, a chemotherapy medicine used to treat non-small cell lung cancer and malignant pleural mesothelioma. It slows cancer cell growth and is administered under oncologist supervision.
Benefits
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Helps slow tumor growth and disease progression
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Improves treatment response in eligible lung cancer patients
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Effective when used alone or in combination therapy
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Well-established chemotherapy option with proven clinical results
Indications and Usage
Alimta 100mg Injection is indicated for:
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Non-squamous Non-Small Cell Lung Cancer (NSCLC)
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Malignant Pleural Mesothelioma
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May be given alone or with platinum-based chemotherapy like cisplatin
Treatment must be initiated and managed by an oncologist.
How it Works
Pemetrexed blocks folate-dependent enzymes needed for DNA and RNA synthesis. This prevents cancer cells from dividing and multiplying, helping control tumor growth.
Dosage & Administration
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Dosage based on body surface area (BSA) and clinical condition
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Given as an intravenous infusion every 3 weeks
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Requires folic acid, vitamin B12, and corticosteroids before treatment
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Must be administered by trained healthcare professionals
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Regular blood tests and kidney function monitoring required
Side Effects
Common side effects:
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Fatigue or weakness
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Nausea, vomiting, appetite loss
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Mouth sores
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Rash or itching
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Low blood cell counts (anemia, neutropenia)
Serious side effects (seek medical care):
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Severe infection or fever
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Kidney problems
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Breathing difficulty
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Severe allergic reaction
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Unusual bleeding or bruising
Warning and Precaution
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Not recommended during pregnancy or breastfeeding
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Avoid use in severe kidney impairment unless advised
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Monitor blood counts, liver & kidney function routinely
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Inform doctor about NSAIDs, blood thinners, or other medications
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Increased risk of infection—report fever or sore throat immediately
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Maintain proper hydration unless medically restricted
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