Written by:
Dr. Sophie Reynolds
Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing
Alecnib 150 mg Capsule
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Description
Alecnib Alectinib 150 mg Capsule is a targeted cancer medicine used to treat ALK-positive metastatic non-small cell lung cancer (NSCLC). It helps slow tumor growth and spread under oncologist supervision.
Benefits
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Specifically targets ALK-driven lung cancer
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Helps slow tumor growth and metastasis
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Proven improvement in progression-free survival
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Effective against brain metastases
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Convenient oral dosing for long-term therapy
Indications and Usage
Alecnib Alectinib 150 mg Capsule is indicated for:
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ALK-positive metastatic non-small cell lung cancer (NSCLC)
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First-line treatment or after progression on previous ALK therapy
Diagnosis must be confirmed by ALK-testing, and treatment supervised by an oncologist.
How it Works
Alectinib blocks the activity of ALK (Anaplastic Lymphoma Kinase) — an abnormal protein that drives cancer growth in certain lung cancers. By inhibiting ALK signaling, it prevents cancer cells from multiplying and spreading.
Dosage & Administration
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Usual adult dose: 600 mg per day (150 mg capsules × 4), divided into two doses
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Take with food, at the same times daily
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Swallow capsules whole—do not crush or open
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Do not stop or change dose without medical guidance
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Requires routine liver, kidney, heart rate, and blood tests
Use only under oncologist supervision.
Side Effects
Common side effects:
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Constipation
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Fatigue
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Swelling in hands or feet
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Muscle pain
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Rash
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Low red blood cell count
Serious side effects (seek urgent care):
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Liver toxicity
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Lung inflammation (pneumonitis)
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Severe muscle damage (high CPK levels)
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Slow heart rate
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Severe anemia
Warning and Precaution
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Not recommended during pregnancy or breastfeeding
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Monitor liver function, CPK levels, heart rhythm, and lung symptoms
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Use caution in patients with kidney or liver disease
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Avoid driving if experiencing dizziness or vision changes
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Inform doctor about all medications to prevent interactions
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Report breathing difficulty, severe fatigue, jaundice, or muscle pain immediately
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