Written by:
Dr. Sophie Reynolds

Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing

Alecensa 150 mg Capsule

Brand Name:   Alecensa
Molecule:   Alectinib
Strength:   150 mg
Quantity:   56 Capsules
Form:   Capsule
Packaging Type:   Bottle
Manufacturer/Marketed By:   Roche
Country of Origin:   Switzerland

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Description

Alecensa 150 mg Capsule contains Alectinib, a targeted anticancer medicine used to treat ALK-positive metastatic non-small cell lung cancer (NSCLC). It helps slow tumor growth and spread under oncologist supervision.

Benefits

  • Targets ALK-driven cancer cells directly

  • Helps slow tumor growth and metastasis

  • Proven improvement in progression-free survival

  • Effective for brain metastases due to strong CNS penetration

  • Convenient oral dosing for long-term therapy

Indications and Usage

Alecensa 150 mg Capsule is indicated for:

  • ALK-positive metastatic non-small cell lung cancer (NSCLC)

  • First-line treatment or after progression on another ALK inhibitor

ALK-positive status must be confirmed through approved diagnostic testing.

How it Works

Alectinib blocks abnormal ALK signaling, a genetic mutation that drives cancer cell growth in certain lung cancers. By inhibiting this pathway, it slows tumor development, spread, and survival.

Dosage & Administration

  • Usual dose: 600 mg per day (150 mg × 4 capsules), divided into two doses

  • Take with food, at consistent times daily

  • Swallow capsules whole—do not crush or open

  • Continue until disease progression or unacceptable toxicity

  • Regular liver, kidney, heart rate, and blood tests are required

Use only under oncologist supervision.

Side Effects

Common side effects:

  • Fatigue or weakness

  • Constipation

  • Swelling in hands or feet

  • Muscle pain

  • Rash

  • Low red blood cell count

Serious side effects (seek urgent care):

  • Liver toxicity

  • Lung inflammation (pneumonitis)

  • Severe muscle damage (high CPK levels)

  • Slow or irregular heartbeat

  • Kidney dysfunction

Warning and Precaution

  • Not recommended during pregnancy or breastfeeding

  • Monitor for liver, lung, muscle, and heart-related side effects

  • Avoid driving if experiencing dizziness or vision changes

  • Inform doctor about all medications to prevent interactions

  • Report breathing difficulty, severe fatigue, jaundice, or muscle pain immediately

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