Agrylin 0.5 mg Capsule

Brand Name: Agrylin

Molecule: Anagrelide

Strength: 0.5 mg

Quantity: 100 Capsules

Form: Capsule

Packaging Type: Bottle

Manufacturer/Marketed By: Takeda Pharmaceuticals

Country of Origin: Japan

Description

Agrylin 0.5 mg Capsule contains Anagrelide, a medicine used to reduce high platelet counts in patients with essential thrombocythemia. It helps lower the risk of blood clots and related complications under medical supervision.

Benefits

Effectively lowers elevated platelet levels
Reduces risk of blood clots, stroke, and heart attack
Helps relieve ET-related symptoms (headache, burning hands/feet)
Oral capsule for convenient long-term treatment

Indications and Usage

Agrylin 0.5 mg Capsule is indicated for:

Essential Thrombocythemia (ET)
Other conditions involving abnormally high platelet counts (as prescribed)

Used to prevent clotting-related complications such as thrombosis and bleeding.

How it Works

Anagrelide reduces platelet counts by inhibiting megakaryocyte maturation in the bone marrow. This decreases platelet production and lowers the risk of dangerous clot formation.

Dosage & Administration

Typical starting dose: 0.5 mg 2–4 times daily, or as prescribed
Dose may be gradually adjusted based on platelet response
Swallow capsules whole with water
Do not skip, exceed, or stop doses without medical advice
Regular platelet count and heart monitoring required

Use only under hematologist supervision.

Side Effects

Common side effects:

Headache
Palpitations
Dizziness
Diarrhea
Nausea
Fluid retention

Serious side effects (seek urgent care):

Chest pain or irregular heartbeat
Shortness of breath
Severe bleeding or bruising
Fainting
Worsening heart disease

Warning and Precaution

Not recommended during pregnancy or breastfeeding
Use cautiously in patients with heart disease, arrhythmia, or liver/kidney impairment
Report chest pain, fainting, rapid heartbeat, or severe bleeding immediately
Avoid alcohol unless approved by the doctor
Inform doctor about blood thinners or heart medications
Not for self-treatment or OTC use