Azadine 100 mg Injection

Description

Azadine 100mg Injection contains Azacitidine, an anticancer medicine used to treat myelodysplastic syndromes (MDS) and certain types of leukemia. It helps restore normal blood cell production and slows abnormal cell growth under specialist supervision.

Benefits

• Helps normalize blood cell production

• Reduces dependence on blood transfusions

• Slows growth of abnormal or cancerous marrow cells

• Improves overall survival in eligible patients

• Well-established first-line therapy for MDS

Indications and Usage

Azadine 100mg Injection is indicated for:

• Myelodysplastic Syndromes (MDS)

• Chronic Myelomonocytic Leukemia (CMML)

• Acute Myeloid Leukemia (AML) (selected patients)

• Patients with abnormal or insufficient blood cell production

How it Works

Azacitidine works by inhibiting abnormal DNA methylation, which helps restore normal function and growth of blood-forming cells in the bone marrow. This slows down cancerous cell proliferation and improves the production of healthy blood cells.

Dosage & Administration

• Administered subcutaneously or intravenously by a healthcare professional

• Dose depends on body surface area and patient condition

• Given in treatment cycles, typically 7 days on, followed by rest

• Not for self-administration

• Requires routine monitoring of blood counts and organ function

Side Effects

Common side effects:

• Nausea, vomiting

• Fatigue or weakness

• Injection-site redness or pain

• Low blood counts (anemia, neutropenia, thrombocytopenia)

• Diarrhea or constipation

Serious side effects (seek urgent care):

• Severe infection or fever

• Unusual bleeding or bruising

• Kidney or liver dysfunction

• Breathing difficulty

• Severe allergic reactions

Warning and Precaution

• Not recommended in pregnancy or breastfeeding

• May cause severe bone marrow suppression—regular monitoring required

• Use cautiously in patients with kidney or liver impairment

• Avoid close contact with people who are sick due to infection risk

• Immediately report fever, uncontrolled bleeding, rash, or shortness of breath

• Inform doctor about all medications, especially chemotherapy or immunosuppressants