Written by:
Dr. Sophie Reynolds

Dr. Sophie Reynolds is a board-certified medical doctor specializing in internal medicine. With over a decade of experience in patient care and medical writing

Bd Zadine 300 mg Tablet

Brand Name:   BD-Zadine
Molecule:   Azacitidine
Strength:   300 mg
Quantity:   14 Tablets
Form:   Tablet
Packaging Type:   Bottle
Manufacturer/Marketed By:   BDR Pharma
Country of Origin:   India

Description

BD Zadine 300 mg Tablet is a prescription medicine containing Azacitidine, a hypomethylating agent used to treat disorders where the bone marrow does not produce healthy blood cells. It is commonly prescribed for myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML), and selected cases of acute myeloid leukemia (AML). The medicine helps reduce transfusion needs, supports healthy cell production, and slows disease progression.

Benefits

  • Improves production of healthy blood cells

  • Reduces dependence on blood transfusions

  • Slows progression of bone marrow disorders

  • Enhances survival and quality of life

  • Convenient oral alternative to injectable azacitidine

Indications and Usage

BD Zadine 300 mg Tablet is indicated for:

  • Myelodysplastic Syndromes (MDS)

  • Chronic Myelomonocytic Leukemia (CMML)

  • Acute Myeloid Leukemia (AML) (specific patient groups)

  • Patients with abnormal, ineffective, or reduced blood cell production

How it Works

Azacitidine reduces abnormal DNA methylation, restoring normal functioning of bone marrow cells. This slows the growth of immature or cancerous cells and supports healthier blood formation.

Dosage & Administration

  • Dose is customized by the treating oncologist

  • Swallow the tablet whole with water

  • Take exactly as per prescribed treatment cycles

  • Do not crush, chew, or break the tablet

  • Regular blood tests required to monitor safety and response

  • Do not skip or stop treatment without medical advice

Side Effects

Common side effects:

  • Fatigue, weakness

  • Nausea, vomiting

  • Constipation or diarrhea

  • Loss of appetite

  • Low blood counts (anemia, neutropenia, thrombocytopenia)

Serious side effects (seek urgent care):

  • Fever or signs of infection

  • Unusual bleeding or bruising

  • Severe abdominal pain

  • Kidney or liver dysfunction

  • Severe allergic reactions

Warning and Precaution

  • Not recommended during pregnancy or breastfeeding

  • Increased risk of infection due to low immunity

  • Use cautiously in patients with kidney or liver disease

  • Avoid contact with sick individuals

  • Report immediately:

    • Fever or chills

    • Unusual bleeding

    • Yellowing of skin or eyes

    • Chest pain or breathing difficulty

  • Inform doctor about all chemotherapy or immunosuppressive drugs being used

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