Alpesib 150 mg Tablet

Description

Alpesib 150 mg Tablet contains Alpelisib, a targeted anticancer medicine used to treat certain types of breast cancer. It helps slow tumor growth in patients with PIK3CA-mutated, HR-positive, HER2-negative disease under oncologist supervision.

Benefits

• Targets tumors with PIK3CA mutation

• Helps slow cancer growth and spread

• May improve progression-free survival

• Oral targeted therapy for convenient dosing

• Effective after endocrine therapy resistance

Indications and Usage

Alpesib 150 mg Tablet is indicated for:

• HR-positive, HER2-negative metastatic or advanced breast cancer

• Confirmed PIK3CA gene mutation

• Used in combination with fulvestrant

• For postmenopausal women and adult men after prior endocrine therapy

Diagnosis and treatment must be supervised by an oncologist.

How it Works

Alpelisib selectively inhibits the PI3K-alpha pathway, which is overactive in cancers with PIK3CA mutations. By blocking this signaling, it reduces cancer cell growth, survival, and resistance to hormonal therapy.

Dosage & Administration

• Typical dose: 150 mg once daily, or as prescribed

• Taken with food, at the same time each day

• Swallow tablets whole—do not crush, chew, or break

• Continue therapy unless disease progression or intolerance occurs

• Requires routine monitoring of blood sugar, liver function, and skin reactions

• Do not adjust or stop dose without oncologist approval

Side Effects

Common side effects:

• High blood sugar (hyperglycemia)

• Diarrhea

• Rash or itching

• Nausea

• Fatigue

• Loss of appetite

Serious side effects (seek urgent help):

• Severe allergic or skin reactions

• Lung inflammation (pneumonitis)

• Severe hyperglycemia or ketoacidosis

• Liver dysfunction

• Dehydration

Warning and Precaution

• Not recommended during pregnancy or breastfeeding

• Use caution in patients with diabetes — high risk of hyperglycemia

• Monitor liver, kidney, and lung function regularly

• Avoid alcohol and high-sugar foods if blood sugar increases

• Inform doctor about all ongoing medications

• Stop treatment and seek help if severe rash, breathing issues, or extreme fatigue occur